| Date | Home | Away | Result |
|---|---|---|---|
| 9/30/25 1:30 PM | Palermo FC | FC Venice | 0-0 |
| 9/30/25 1:30 PM | Juve Stabia | Mantova 1911 | 2-1 |
| 9/30/25 1:30 PM | Padova Calcio | US Avellino | 2-2 |
| 9/30/25 1:30 PM | AC Reggiana 1919 | Spezia Calcio | 1-1 |
| 9/30/25 1:30 PM | Virtus Entella | SSC Bari | 2-2 |
| 9/30/25 1:30 PM | Frosinone Calcio | FC Cesena | 3-1 |
| 10/1/25 1:30 PM | Pescara Calcio | FC Südtirol | 1-1 |
| 10/1/25 1:30 PM | Sampdoria Genua | US Catanzaro 1929 | 0-0 |
| 10/1/25 1:30 PM | Carrarese Calcio 1908 | Modena FC | 0-0 |
| 10/1/25 1:30 PM | FC Empoli | AC Monza | 1-1 |